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The Difference Between Squalane and Squalene


Disclaimer: The information contained on this site is general in nature and for informational purposes. It is not meant to substitute for the advice... read more

Disclaimer: The information contained on this site is general in nature and for informational purposes. It is not meant to substitute for the advice provided by your own physician or other medical professional. None of the statements on this site are a recommendation as to how to treat any particular disease or health-related condition. If you suspect you have a disease or health-related condition of any kind, you should contact your health care professional immediately. Please read all product packaging carefully and consult with a healthcare professional before starting any diet, exercise, supplementation or medication program. Cosmetic products have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent disease. read less

The Difference Between Squalane and Squalene

Reading an ingredient label can seem like a college exam. A one letter change to an ingredient can mean a difference in safety, effect or potency. It almost makes you want to just put it back on the shelf and rub plain ol’ coconut oil on your face. Which wouldn’t be the worst thing…

A case when a change in letter isn’t quite so dramatic, but still has caused some confusion, is with the difference between squalane and squalene. We’ll start with some background on this ingredient, which is found in skin care products, as well as vaccinations.

The Chemistry

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Squalene is a fat-soluble anti-oxidant that is naturally produced during cholesterol synthesis and occurs in the skin. Like similarly structured molecules such as Vitamin E, squalene can help protect against environmental stressors.


Before we dive into the difference between squalene and squalane, let’s talk about why this ingredient is important to our annually celebrated predators of the sea. Some deep sea sharks depend on squalene it for their survival. Up to 80% of the oil in these sharks’ livers is comprised of squalene, which is even more notable considering that a shark’s liver makes up 25% of its mass. Squalene helps the body utilize oxygen more efficiently, which is important when you dwell at the bottom of the ocean, where it is scarce.

Squalene in Skin Care

Squalene has proven itself to be an effective moisturizer and emollient agent for producing products that have a nice, spreadable texture. It also aids in the absorption of other nutrients, thus can be used to synergistically improve the effectiveness of a product.

Squalene used for skin care is often harvested straight from the source, by hunting sharks and extracting oil from their liver. Concern over this exploitative process has led to the use of other sources of squalene, such as olives and sugarcane. Over the last 40 years that there has been a market for this ingredient, many of the deep sea species of sharks with high amounts of squalene have been hunted to near extinction. Not only is it not humane, it’s not sustainable.

For our organic skin care, we only use olive-derived squalene.

The Difference Between Squalane and Squalene

Squalene isn’t stable enough for use in products intended to be kept on the shelves for some time, like skin care products. Squalane is derived from squalene, and is the more stable form of this molecule, as well as being colorless and odorless.

We blend olive-derived squalane with CoQ10 in the form of Ubiquinone – a fat soluble nutrient- to create a form of CoQ10 that your skin can absorb easily! Enjoy the moisturizing and absorption-boosting properties of squalane when you use our Anti-Aging Eye Cream.

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Please Note: Due to our interest in FDA cosmetic guidelines compliance, all blog comments are reviewed before posting and may be removed from Annmarie Skin Care website or edited for claims that do not meet FDA standards.

COMMENTS ( 1 and counting )
  1. Not entirely informative. Squalane is also produced without shark liver oil.