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Plant Stem Cells—the Latest Scientific Breakthrough in Anti-Aging Skin Care

Have you noticed signs of aging in your skin? Do you have more dullness, dryness, wrinkles, or sagging than you did five, ten, or fifteen years ago?

If so, you’re not alone. All of us experience the aging process, which includes thinning, age spots, loss of strength and elasticity, and increased dryness because of reduced oil production.

Most of us don’t like the idea of showing our age, however, and seek solutions to help slow down and conceal the signs of aging on the skin. Though we already have some key tools to use in our fight against the aging process, including natural oils that deeply hydrate, essential fatty acids that plump and firm, and nutrients that help protect from outside elements, science has zoomed in on another powerful anti-aging ally: the stem cell.

Though we’ve heard the debates about using human stem cells in research, the exciting thing about stem cells in skin care is that we can use specialized options from plants to encourage the results we want to see in skin, without having to use raw materials that challenge our ethical standards.

At Annmarie Gianni Skin Care, we’re excited to talk about stem cells, because we’ve found the perfect ones to use in our new Repair Serum. They come from a clean, natural, and environmentally friendly source, and have shown in studies to help stimulate regeneration and repair in your skin, to reveal a smoother, tighter, more youthful complexion.

Stem CellsPlant stem cells can help stimulate skin to regenerate and repair itself.

What are Stem Cells?

You’ve probably heard about “stem cells” in the news. Most of the media coverage has been about embryonic stem cells, which come from unfertilized embryos, and are known to have the capacity to form any type of tissue in the body and to regenerate failing organs. Scientists are very excited about these types of stem cells because of their potential in fighting disease.

But did you know that your adult body is full of stem cells as well? They are embedded in every organ system, including your skin, and are there for one primary duty—regeneration. That means if any part of your body is injured, these stem cells migrate to the location and go to work repairing the damage and regenerating tissues.

The skin is one of the primary locations where we see stem cells at work all the time. Because it is constantly renewing itself, sloughing off old dead cells and replacing them with younger, newer cells, it’s in constant need of stem cells to help carry out this regeneration.

In fact, according to a study published in 2003, the outer layer of skin is consistently renewing and repairing itself “by constant proliferation of a single inner layer of rapidly dividing progeny of stem cells.” A more recent study published in 2012 found the existence of a new population of stem cells “that give rise to progenitor cells that ensure the daily maintenance of the epidermis [outer layer] and demonstrate the major contribution of epidermal stem cells during wound healing.”

Skin stem cells have a huge job, then, as according to the 2003 study, “Because human epidermis turns over every 2 weeks…the self-renewing capacity of epidermal stem cells is enormous.”

What Happens to Stem Cells as We Age

Because of their ability to regenerate tissues, stem cells are vital in skin repair. In the 2012 study mentioned above, scientists discovered that “only stem cells are capable of extensive tissue regeneration and undergo major expansion during this repair process….”

If you suffer wounds on your skin, then, which all of us do, you need stem cells to help repair those wounds and regenerate new skin. Have you noticed how a baby’s skin will heal without scarring? That’s a sign of new stem cells that are capable of complete repair.

Adult stem cells also work to repair and regenerate skin tissues, but as we age, sun damage, environmental elements, and other factors can weaken and reduce the skin’s supply of key stem cells. In fact, as we get older, most adult stem cell populations either decline or lose the ability to do their jobs as well as they used to.

That means that first, skin renewal slows down. You’ve probably noticed that your skin doesn’t appear as dewy or young-looking as it used to. That’s a clear sign that it isn’t turning over as quickly as it once did, which is one reason we advocate regular exfoliation as you age, to help the skin slough off those dead cells and reveal the healthier-looking younger ones underneath. Regular exfoliation can also encourage the skin to continue to renew itself.

A decline in skin stem cells also means that critical repair of wounds—which include redness, acne scars, age spots, sun damage, and sagging collagen and elastin—no longer takes place as quickly or efficiently as it once did. So your acne scar may take weeks or even months to fade. Meanwhile, other wounds for the same repair process, like fine lines and wrinkles, may remain unaddressed.

How Plant Stem Cells Can Help

Finding help from the plant world is not new for Annmarie Gianni Skin Care. We have long known the power of plants to help protect and restore the skin, as evidenced by our other established formulas.

So when looking for ways to encourage skin repair and regeneration, it was no surprise that we found a similar helping hand from plant stem cells. Just like humans, plants have stem cells that work to form different tissues and organs in the plant itself, and then continue to create new cells to regenerate and repair the plant as it lives its life. In fact, because plants cannot escape the danger around them, it has been argued that their stem cells may be even stronger than our own, capable of withstanding all types of environmental stress to continue to regenerate and restore the plant’s various systems.

But can plant stem cells really help our human stem cells? Research shows they can, and here’s how. It’s not a matter of a simple swap. We’re not replacing our stem cells with those from a plant. What the plant stem cells can do when we apply them to the skin, however, is to protect our own stem cells so they live longer, and stimulate them to get active again.

What does that mean to you? Reduced signs of aging!

Our Unique Stem Cells from Citrus

In seeking out a source of stem cells for our new product, Repair Serum, we wanted something that would be non-irritating to the skin and to our sensibilities. That’s why when we saw the tests behind citrus stem cells, we were convinced they were the right ones for our customers. Not only are they from a non-human and non-animal source, but they have solid studies behind them.

Here are some of the results that citrus-based stem cells were able to create on the skin:

  • Improvement in skin structure: In laboratory tests, citrus stem cells improved the structure of skin, encouraging the strengthening of collagen and elastin.
  • Stimulation of TGK: TGK is an essential enzyme for the outer layer of skin—the more you have, the better your skin is able to rebuild itself as it should, resulting in a smoother appearance.
  • Stimulation of fibroblasts: Fibroblasts are cells in connective tissues that produce collagen and other fibers, and are responsible for forming the structural framework of skin—as we age, they decline in number, leading to sagging and wrinkles. Fibroblasts are produced by stem cells. Our citrus stem cells showed in studies to stimulate the production of fibroblasts, which helps to “shore up” skin structure, reducing sagging and wrinkles.
  • Encourage cell turnover: In living organism tests, our citrus stem cells encouraged skin cell turnover, resulting in smoother, softer skin.
  • Improved “microrelief”: In the language of science, the “microrelief” refers to the supportive structure of skin. A disorganized and damaged microrelief is like the aged springs in a mattress—stretched out, weakened, and less able to hold skin up. That means wrinkles, expression lines, and folds. According to a 2003 study, “Wrinkles result from structural changes in the epidermis, dermis, and hypodermis.” Our citrus stem cells encouraged a healthier microrelief better able to support the skin, as evidenced by the before (T0) and after shot (T56) below, resulting in fewer wrinkles and fine lines.
  • Improved elasticity: Elasticity is skin’s ability to “spring back” after you smile, frown, or make other expressions. Over time, we lose that ability, which is why we have lines showing up on our faces. Our citrus stem cells improved elasticity, helping skin to recover and appear up to 12 years younger!


You Can Try it Now for Free!

As you can see, stem cells are at the cutting edge of research on anti-aging skin care. We’re super excited to have this progressive ingredient in our new Repair Serum, and can’t wait to hear about the results you experience after using it.

If you hurry, you can get your FREE sample with any order you place from now until March 16th, 2013. Don’t wait—try this breakthrough new product today and let us know what you think!

Do you suffer from skin damage? Please share your story.

* * *

Laura Alonso and Elaine Fuchs, “Stem cells in the skin: waste not, want not,” Genes & Dev. 2003, 17:1189-1200,

Libre de Bruxelles, Universit (2012, September 3). Newly identified stem cell population in skin’s epidermis responsible for tissue repair. ScienceDaily. Retrieved March 8, 2013, from­ /releases/2012/09/120903142959.htm.

Pierard GE, et al., “From skin microrelief to wrinkles. An area ripe for investigation,” J Cosmet Dermatol, 2003 Jan;2(1):21-8,

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COMMENTS ( 4 and counting )
  1. Suellen says:

    Wow! I can’t wait to try this! Please let me take a moment to thank you for this great explanation of your new product. I am not a scientist. So often when a company explains their product, it falls at the outer spectrum… either to scientific for the average reader (me, so I give up and quit reading) or it becomes a 2 sentence explanation that is so simplistic it gives you no information at all.

    This article was so educational and stated in such an understandable way that I just had to thank you. I will continue to use your products, which I completely love and look forward to getting my sample of this one as well.



  2. Kellie says:

    I second Suellen. The above explanation is fantastic. It’s educational, complete and easy to understand. I love your products. I have had so many compliments on the appearance of my skin since I’ve started using the entire anti-aging line. I feel more confident, my skin glows and is simply radiant. I am so grateful that you’ve spent the painstaking time to research and only bring the absolute best products to the consumer. We deserve to be told the truth about what’s in our products and we deserve to have the very best. God created absolute incredible bodies to regenerate and heal itself, why not give it the best care possible.
    Thank you, thank you, thank you from the bottom of my heart!!!

  3. Marc says:

    Dear Annmarie,

    Thank you for your interest in the exciting field of plant stem cells. as a matter of full disclosure, I work in that field and how to produce plant stem cells through plant cell culture. What is so unique and efficacious in (some) plant stem cells is their ability to “over” produce bio-actives that trigger the efficacy. I suspect that citrus being traditionally reasonably rich in vitamin C, flavonoids and lycopene, the plant cell ingredient that you formulate also contains some. The efficacy of the bio-actives within the plant cell and their concentration (not all plant stem cells are equal) is what will grant efficacy. you are in a great position to further help your clients understand how things work with that unique phenomenon of Nature.

    Feel free to take a look at to further discover the science behind plant cell culture.

    Wishing you the best success,

  4. CJL says:

    where do i buy it, what about human stem cell? or animal?